ISSN 1662-4009 (online)

ey0019.10-5 | New paradigms | ESPEYB19

10.5. Heterogeneity of type 1 diabetes at diagnosis supports existence of age-related endotypes

T. Harkonen Parviainen , Ilonen J. , But A. , M. Knip and

Diabetes Care. 2022 Apr 1;45(4):871-879. https://pubmed.ncbi.nlm.nih.gov/35147706/Brief Summary: This Finnish cross-sectional register-based study of 6015 youth with new onset type 1 diabetes (T1D) explored potential differences in clinical, autoimmune and genetic characteristics across three age groups: <7, 7-12 and ≥13 years. Significant differences emerged primarily between the...

ey0016.10-10 | (1) | ESPEYB16

10.10. Sex as a determinant of type 1 diabetes at diagnosis

M Turtinen , T Harkonen , A Parkkola , J Ilonen , M Knip , Pediatric Diabetes Register Finnish

To read the full abstract: Pediatr Diabetes. 2018 Nov;19(7):1221–1228Despite good metabolic control some patients with type 1 diabetes (T1D) may develop comorbidities early while others despite high HbA1c levels remain free of complications for long durations. Risk factors for T1D complications are both of intrinsic (e.g. genetic) and extrinsic (e.g. environmental) origin. Amongst t...